Alvis Brazma, European Bioinformatics Institute
Track: Keynote
Date: Thursday, February 06
Time: 8:30am - 9:15am
Location: California Ballroom
Microarray data are already providing important insights into mechanisms of cell development, differentiation and disease, and the networks of gene regulation. Brazma discusses current efforts by the Microarray Gene Expression Data society to make maximum use of the vast amounts of existing and potential data generated by this technology by adopting standards for describing and annotating microarray experiments, and by establishing an infrastructure for sharing these data.
The Microarray Gene Expression Data (MGED) society is an international organization for facilitating sharing of functional genomics and proteomics microarray data. MGED was initially established as a grass-roots movement in 1999, at a meeting in Cambridge, UK. MGED has developed recommendations called Minimum Information About a Microarray Experiment, known as MIAME, with the goal to outline the minimum information required to interpret unambiguously and potentially reproduce and verify array-based gene expression monitoring experiments. A standard microarray data exchange format, MAGE-ML, which is able to capture information specified by MIAME, has recently became an Adopted Specification of the OMG standards group. Many organizations, including EBI, Rosetta Biosoftware, Agilent, Affymetrix, and Iobion, have contributed ideas to the developed standards. ArrayExpress is a public repository for microarray gene expression data at the EBI, which implements MGED standards.
Download presentation file
