O'Reilly Bioinformatics Conference 2003

O'Reilly Bioinformatics Technology Conference.

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Session
Engineered Gene Networks
Jeff Hasty, Department of Bioengineering, University of California, San Diego

Track: Bioinformatics Overview
Date: Tuesday, February 04
Time: 2:15pm - 3:00pm
Location: California Ballroom A & B
A central focus of post-genomic research will be to understand how cellular phenomena arise from the connectivity of genes and proteins. This connectivity generates molecular network diagrams that resemble complex electrical circuits, and a systematic understanding will require the development of a mathematical framework for describing the circuitry. From an engineering perspective, the natural path toward such a framework is the construction and analysis of the underlying submodules that constitute the network.

Hasty's talk focuses on recent experimental advances that have made this approach feasible through the design and implementation of synthetic gene networks amenable to mathematical modeling and quantitative analysis. These developments have signalled the emergence of a gene circuit discipline, which provides a framework for predicting and evaluating the dynamics of cellular processes.