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Practical Innovation at BioCon 2003

Poster Session

Profiling Genomes with Genomic Signature Tags (GSTs)

By Sean McCorkle
Bioinformaticist, Brookhaven National Laboratory

Genome Signature Tags (GSTs) are a versatile DNA-based sequencing system for profiling genomes in complex communities. 21-bp tags are positionally defined by restriction enzymes, whose selection allows control the number of tags per genome. Small tag counts are sufficient to identify known species. Oversampling allows isolation of novel species, along with relative abundances information.

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